Avoid becoming pregnant while using nicotine patches.
Remove the transdermal patch 2 hours before engaging in prolonged strenuous exercise. See your Doctor before using if you: Have ever had a heart attack, angina, heart arrhythmias or a stroke. Have or have ever had high blood pressure, heart disease, thyroid problems, blood circulation or stomach problems, stomach ulcers, kidney or liver disease, diabetes requiring insulin, stoke or treatment of circulation disorders of the brain, allergies to drugs, or have had any allergies to adhesive tape or bandages. The following to be included on package insert: Remove the nicotine patch and consult your doctor if you experience irregular heartbeat, chest pain, palpitations or leg pain occurs or if severe or persistent stomach upset (indigestion, heartburn) develops.